New UK Alzheimer’s study looking for volunteers

The University of Kentucky’s Sanders-Brown Center on Aging Alzheimer’s Disease Center is participating in a new study for people with Alzheimer’s disease, the Chase study.

By volunteering for this study, you can help the center learn how to better treat Alzheimer’s disease with medicines that are already available for use in the U.S.

The purpose of the research is to gather information on how safe the maximum tolerated dose of donepezil is when given with another FDA approved medication.

The other FDA approved medication is being used in the study to see if it will reduce the side effects of donepezil and allow a higher dose to be used that may be more effective in treating the symptoms of Alzheimer’s disease.

Researchers are looking for people who:
• Are between the ages of 50-89
• Have been taking Aricept (Donepezil) 10 mg daily for at least 12 weeks
• Have a partner available to attend clinic appointments and help with medication
• Are taking stable medications for at least four weeks prior to the screening
• Willing and able to undergo clinic assessments (for example – blood and urine lab tests,
neuropsychological testing, ECG and bladder ultrasound).

For more information, contact Sarah D. Tarrant at (859) 323-1331 or at sarah.tarrant@uky.edu