Long-lived parents could mean a healthier heart into your 70s
The longer our parents lived, the longer we are likely to live ourselves, and the more likely we are to stay healthy in our 60s and 70s. Having longer-lived parents means we have with much lower rates of a range of heart conditions and some cancers.
The major study, funded by the Medical Research Council and involving almost 190,000 participants in the UK Biobank, is the largest of its kind. The UK Biobank is a major health resource with a half million participants aged 45-69. It found that our chances of survival increased by 17 per cent for each decade that at least one parent lives beyond the age of 70.
The study, published today in the Journal of the American College of Cardiology, was led by the University of Exeter and involved an international team of academics from the University of Cambridge (UK), UConn Center on Aging at UConn Health in Connecticut, USA, the French National Institute of Health, and the Indian Institute of Public Health. It found evidence showing for the first time that knowing the age at which your parents died could help predict your risk not only of heart disease, but many aspects of heart and circulatory health.
The researchers used data on the health of 186,000 middle-aged offspring, aged 55 to 73 years, followed over a period of up to eight years. The team found that those with longer lived parents had lower incidence of multiple circulatory conditions including heart disease, heart failure, stroke, high blood pressure, high cholesterol levels and atrial fibrillation. For example, the risk of death from heart disease was 20% lower for each decade that at least one parent lived beyond the age of 70 years. In addition, those with longer lived parents also had reduced risk of cancer; 7% reduced likelihood of cancer in the follow-up per longer-lived parent.
Although factors such as smoking, high alcohol consumption, low physical activity and obesity were important, the lifespan of our parents was still predictive of disease onset after accounting for these risks.
Dr Janice Atkins, a Research Fellow in the Epidemiology and Public Health group at the University of Exeter Medical School and lead author on the paper, said: “To our knowledge, this is the largest study to show that the longer your parents live, the more likely you are to remain healthy in your sixties and seventies. Asking about parents’ longevity could help us predict our likelihood of ageing well and developing conditions such as heart disease, in order to identify patients at higher or lower risk in time to treat them appropriately.”